research
 


Research Projects -
Uro-oncology


  • The investigation of suspected alterations in cytochrome activity in patients with bladder cancer by a validated drug-cocktail protocol.
  • Investigations into the activity of cytochrome P450 isoenzymes in bladder cancer by phenotypic and genetic methods and any association with cytochrome activity and tumour stage or grade, recurrence, progression, survival and genetic markers.
  • A retrospective study assessing the implementation of an enhanced recovery protocol for patients undergoing radical cystectomy at Southmead Hospital.
  • Investigating the expression and therapeutic potential of VEGF165b, an inhibitory splice variant of vascular endothelial growth factor (VEGF) in bladder cancer.
  • VEGF165b, an inhibitory effect on angiogenesis in transitional cell carcinoma of the bladder.
  • Volatile organic compounds in the rapid diagnosis of bladder cancer.
  • Investigating a novel urine-based non-invasive screening test for prostate cancer, based upon an early morning urine sample.
  • Study to assess whether pre-exposure of prostate cancer cells to the dietary chemopreventive agents, lycopene or green tea extract affects their subsequent sensitivity to radiation therapy.
  • Cost effectiveness and quality of life: A comparison of three treatment modalities for early stage prostate cancer.
  • A survey of Primary Care Trust provision of brachytherapy.
  • The role of insulin-like growth factor, its binding proteins, epidermal growth factor and androgens on prostate cancer cells.
  • Mass spectrometry of urine to identify markers of prostate cancer.
  • Complete cytokeratin profile of human prostate.
  • Audit of usage of the Department of Health age related guidelines for prostate specific antigen amongst United Kingdom urologists.
  • Randomised Controlled Trial of alpha blocker versus placebo in patients being treated with 3-D conformal radiotherapy for localised prostate cancer.
  • Project with the South West Public Health Observatory and Cancer Registry Office into the correlation between clinical and pathological staging of prostate cancer and lymph node dissection in radical prostatectomy.
  • Pain controlled post-prostatectomy: epidural versus PCA.
  • Protect Study and prostate cancer screening to compare effectiveness of treatment versus "watchful waiting".
  • UK audit of Department of Health Prostate Specific Antigen guidelines.
 
 
^ Go to Top
 
< Return to Research Programmes
 
 
 
only search this site

 
    
Page Last Updated 11 October, 2009 © Bristol Urological Institute - North Bristol NHS Charitable Funds Charity Registration No: 1055900